Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035106 | 0.86 | COMT (0.36) | KMT2AMAPTPOLBMEN1SMN1; SMN2 | |
| SCHEMBL8022533 | 0.85 | G6PD (0.38) | G6PDCRHBPCRHR2KMT2APYGL | |
| SCHEMBL8038459 | 0.83 | TRPV1 (0.39) | G6PDCRHBPCRHR2MAPTSMN1; SMN2 | |
| SCHEMBL8036155 | 0.82 | MEN1 (0.42) | G6PDCRHBPCRHR2KMT2APYGL | |
| SCHEMBL8041330 | 0.82 | G6PD (0.34) | G6PDCRHBPCRHR2KMT2AMAPT | |
| SCHEMBL8032230 | 0.81 | MAPT (0.38) | G6PDCRHBPCRHR2KMT2APYGL | |
| SCHEMBL8035129 | 0.79 | ALDH1A1 (0.39) | KMT2APYGLMAPTPOLBMEN1 | |
| SCHEMBL8025556 | 0.76 | NPSR1 (0.42) | G6PDCRHBPCRHR2KMT2AMAPT | |
| SCHEMBL8023142 | 0.75 | ALDH1A1 (0.39) | KMT2AMAPTPOLBMEN1SMN1; SMN2 | |
| SCHEMBL8023948 | 0.74 | PYGL (0.46) | KMT2APYGLMAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |