Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033765 | 0.81 | CNR2 (0.43) | TDP1CNR2EPHX2PDE4DMAPK14 | |
| SCHEMBL8040276 | 0.78 | SMO (0.34) | EPHX2PDE4DSLC6A9GAA | |
| SCHEMBL8036155 | 0.71 | MEN1 (0.42) | TDP1 | |
| SCHEMBL8025559 | 0.69 | MAPT (0.37) | — | |
| SCHEMBL8035162 | 0.68 | ALDH1A1 (0.41) | EPHX2PDE4D | |
| SCHEMBL8037015 | 0.67 | ALDH1A1 (0.45) | TDP1 | |
| SCHEMBL8034312 | 0.67 | TBXA2R (0.38) | EPHX2PDE10A | |
| SCHEMBL8038220 | 0.67 | PPIA (0.42) | GAA | |
| SCHEMBL8023142 | 0.66 | ALDH1A1 (0.39) | — | |
| SCHEMBL8038463 | 0.66 | EPHX2 (0.39) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |