Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037266 | 0.91 | GABRA2 (0.45) | ADORA3ALDH1A1MAPTPKMKDM4E | |
| SCHEMBL4009387 | 0.86 | DPP4 (0.44) | ADORA3ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL4009335 | 0.82 | ALDH1A1 (0.38) | ADORA3ALDH1A1MAPTPKMKDM4E | |
| SCHEMBL8040651 | 0.81 | ADORA3 (0.47) | ADORA3ALDH1A1MAPTPKMKDM4E | |
| SCHEMBL4009391 | 0.79 | ALDH1A1 (0.41) | ADORA3ALDH1A1MAPTPKMKDM4E | |
| SCHEMBL8040514 | 0.78 | KDM4E (0.51) | ALDH1A1MAPTPKMKDM4ERAB9A | |
| SCHEMBL12929596 | 0.77 | ALDH1A1 (0.65) | ALDH1A1MAPTPKMRAB9ATP53 | |
| SCHEMBL12929410 | 0.77 | ADORA3 (0.57) | ADORA3ALDH1A1MAPTKDM4ERAB9A | |
| SCHEMBL8042776 | 0.76 | TSHR (0.48) | ADORA3ALDH1A1MAPTPKMKDM4E | |
| SCHEMBL8025238 | 0.75 | RXRA (0.48) | ADORA3ALDH1A1MAPTPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |