Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | PPARA | Q07869 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL8039218 | 0.88 | GSR (0.43) | ALOX5 | |
| Cyclohexylamine SCHEMBL7801468 | 0.86 | HCAR2 (0.39) | HCAR2ALOX5ALDH1A1PPARA | |
| Benzaldehyde SCHEMBL8035694 | 0.84 | KIF11 (0.42) | KIF11GRIK1GRIK2ALDH1A1PPARG | |
| Cyclohexylamine SCHEMBL7800167 | 0.83 | HCAR2 (0.36) | HCAR2ALOX5ALDH1A1 | |
| 4-Hydroxybenzaldehyde SCHEMBL8037281 | 0.81 | ALDH5A1 (0.41) | KIF11SLC1A3SLC1A2SLC1A1GRIK1 | |
| 4-Hydroxybenzaldehyde SCHEMBL8037276 | 0.81 | ALDH5A1 (0.41) | KIF11SLC1A3SLC1A2SLC1A1GRIK1 | |
| Cyclohexylamine SCHEMBL8037416 | 0.81 | ALDH1A1 (0.47) | KIF11GRIK1GRIK2ALDH1A1 | |
| Cyclohexylamine SCHEMBL8037514 | 0.81 | GRIK1 (0.42) | KIF11GRIK1GRIK2ALDH1A1 | |
| Cyclohexylamine SCHEMBL8037697 | 0.81 | GRIK1 (0.41) | KIF11GRIK1GRIK2ALDH1A1 | |
| Cyclohexylamine SCHEMBL8037511 | 0.81 | GRIK1 (0.42) | KIF11GRIK1GRIK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |