Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.40 |
| ▸ | MAOA | P21397 | 11/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 9/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036369 | 0.88 | MAOB (0.42) | MAOBMAOAMAPK1CYP2C19KDM1A | |
| Hydrochloric Acid SCHEMBL8038381 | 0.86 | MAOB (0.43) | MAOBMAOAMAPK1CYP2C19KDM1A | |
| SCHEMBL8034589 | 0.78 | RORC (0.42) | KDM1A | |
| SCHEMBL8036360 | 0.78 | ALOX15 (0.50) | MAOBMAOAMAPK1KDM1A | |
| SCHEMBL8036366 | 0.75 | MLYCD (0.47) | MAPK1CYP2C19 | |
| SCHEMBL8040665 | 0.75 | POLB (0.56) | MAPK1CYP2C19 | |
| SCHEMBL8461900 | 0.71 | TSHR (0.46) | — | |
| SCHEMBL10981382 | 0.70 | KDM1A (0.53) | MAOBMAOAMAPK1CYP2C19KDM1A | |
| SCHEMBL106104 | 0.68 | ALDH1A1 (0.39) | — | |
| Benzene SCHEMBL10386399 | 0.67 | ALDH1A1 (0.54) | MAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159973-A | Aromatic amides, their preparation process, the compositions containing them and their use as pesticides | HOECHST SCHERING AGREVO S.A. (FR) | 2000-12-12 | — | — | US | disclosed |
| US-6013837-A | E.G.,4-(2-(3,4,5-TRICHLORO PHENYL) 1-FLUOROCYCLOPROPYL)-N-(2-METHYL PHENYL)BENZAMIDE; PARTICULAR USE AGAINST ARTHROPODS, HELMINTHS AND MOLLUSCS; INSECTICIDES; ACARICIDES; NEMATICIDES; PHOTOSTABILITY; NONTOXIC TO MAMMALS | HOECHST MARION ROUSSEL (FR) | 2000-01-11 | — | — | US | disclosed |