Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033004 | 0.93 | HDAC3 (0.50) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL8030835 | 0.85 | USP2 (0.50) | HDAC1HDAC3HDAC2HSD17B10USP2 | |
| SCHEMBL8040684 | 0.85 | HDAC1 (0.53) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL8039052 | 0.82 | HDAC1 (0.46) | HDAC1MAPTMAPK1 | |
| SCHEMBL8038398 | 0.81 | TMIGD3 (0.46) | HDAC1MAPTMAPK1 | |
| SCHEMBL8038965 | 0.81 | TMIGD3 (0.50) | MAPTSMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL28428243 | 0.81 | ADORA3 (0.56) | MAPTSMN1; SMN2MAPK1LMNAKDM4E | |
| SCHEMBL8034917 | 0.79 | GPR119 (0.54) | MAPTSMN1; SMN2KMT2ALMNATSHR | |
| SCHEMBL8032750 | 0.78 | ADORA3 (0.49) | MAPTMAPK1LMNAKDM4E | |
| SCHEMBL8021617 | 0.76 | TMIGD3 (0.45) | MAPTSMN1; SMN2KMT2AMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099177-A1 | AMINO IMIDAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-13 | — | — | WO | disclosed |