Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038965 | 0.85 | TMIGD3 (0.50) | ADORA3TMIGD3 | |
| SCHEMBL28428243 | 0.85 | ADORA3 (0.56) | ALDH1A1ADORA3TMIGD3 | |
| SCHEMBL8038447 | 0.85 | HDAC1 (0.57) | USP2ALDH1A1TSHRHSD17B10HDAC3 | |
| SCHEMBL8032750 | 0.82 | ADORA3 (0.49) | ADORA3TMIGD3 | |
| SCHEMBL8034917 | 0.81 | GPR119 (0.54) | ALDH1A1TSHRATRFLT3 | |
| SCHEMBL8038395 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ADORA3TMIGD3 | |
| SCHEMBL8039052 | 0.80 | HDAC1 (0.46) | HDAC1ADORA3TMIGD3 | |
| SCHEMBL8021617 | 0.80 | TMIGD3 (0.45) | ALDH1A1ADORA3TMIGD3 | |
| SCHEMBL8039049 | 0.80 | TMIGD3 (0.45) | ADORA3TMIGD3 | |
| SCHEMBL8034915 | 0.80 | MAPT (0.46) | ALDH1A1ADORA3TMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099177-A1 | AMINO IMIDAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-13 | — | — | WO | disclosed |