Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043493 | 0.88 | PLA2G1B (0.45) | NPSR1KDM4EPLA2G1BATG4BRXRA | |
| SCHEMBL8040593 | 0.82 | TSHR (0.47) | ALDH1A1LMNANPSR1TSHRMEN1 | |
| SCHEMBL8025168 | 0.81 | TSHR (0.44) | CASP3ALDH1A1LMNANPSR1TSHR | |
| SCHEMBL8038516 | 0.80 | NPSR1 (0.39) | ALOX15ALDH1A1NPSR1TSHRKDM4E | |
| SCHEMBL8038586 | 0.78 | ALDH1A1 (0.45) | ALDH1A1LMNANPSR1TSHRMEN1 | |
| SCHEMBL8040307 | 0.78 | GABRA2 (0.49) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL5127225 | 0.78 | MEN1 (0.46) | CASP3ALOX15ALDH1A1LMNANPSR1 | |
| SCHEMBL8037289 | 0.76 | GABRA2 (0.44) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL8037126 | 0.76 | PLA2G1B (0.41) | ALOX15ALDH1A1LMNANPSR1TSHR | |
| SCHEMBL8031870 | 0.74 | SLC6A3 (0.42) | ALOX15ALDH1A1LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |