Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034844 | 0.88 | CASP3 (0.46) | PLA2G1BATG4BRXRANR4A2ADORA3 | |
| SCHEMBL8037126 | 0.87 | PLA2G1B (0.41) | PLA2G1BATG4BRXRANR4A2PDE5A | |
| SCHEMBL8030010 | 0.81 | RXRA (0.47) | RXRANR4A2ACP1FABP3FABP4 | |
| SCHEMBL4011568 | 0.80 | FABP4 (0.42) | RXRANR4A2FABP3FABP4FABP5 | |
| SCHEMBL8038516 | 0.77 | NPSR1 (0.39) | PLA2G1BATG4BPDE5AACP1CNR1 | |
| SCHEMBL8040520 | 0.76 | NPSR1 (0.43) | PLA2G1BATG4BRXRANR4A2ACP1 | |
| SCHEMBL5961069 | 0.76 | FABP3 (0.49) | RXRANR4A2FABP3FABP4FABP5 | |
| SCHEMBL8037000 | 0.76 | RXRA (0.47) | RXRANR4A2FABP3FABP4FABP5 | |
| SCHEMBL4151850 | 0.74 | FABP3 (0.48) | RXRANR4A2ACP1FABP3FABP4 | |
| SCHEMBL14914473 | 0.74 | PPARG (0.54) | ADORA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |