Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 12/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025896 | 0.77 | DRD2 (0.44) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7851700 | 0.77 | KDM4E (0.54) | MTNR1AMTNR1BKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7504744 | 0.76 | MTNR1A (0.40) | GRM5GRM1HSP90AA1MTNR1AMTNR1B | |
| SCHEMBL7504730 | 0.74 | ALOX5 (0.43) | GRM5GRM1MTNR1AMTNR1BTUBB4A | |
| SCHEMBL7333499 | 0.68 | NOTUM (0.49) | HSP90AA1MTNR1AMTNR1BKMT2ASMN1; SMN2 | |
| SCHEMBL7506393 | 0.67 | SMN1; SMN2 (0.35) | HSP90AA1MTNR1AMTNR1BKMT2ASMN1; SMN2 | |
| SCHEMBL8039635 | 0.66 | KDM4E (0.56) | HSP90AA1KMT2ASMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL7509408 | 0.65 | KDM4E (0.38) | GRM5TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19382614 | 0.62 | CYP1A2 (0.61) | MTNR1AKMT2ASMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL25366082 | 0.61 | ALOX5 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048868-A | CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS; ANTIDEPRESSANTS | CEMAF (FR) | 2000-04-11 | — | — | US | disclosed |