Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | SELL | P14151 | 1/20 | 0.31 |
| ▸ | SELP | P16109 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028359 | 0.88 | SMN1; SMN2 (0.35) | TAS1R3TAS1R1TAS1R2TTRDRD2 | |
| SCHEMBL8035683 | 0.81 | SMYD3 (0.32) | TAS1R3TAS1R1TAS1R2COMT | |
| SCHEMBL8035622 | 0.81 | COMT (0.37) | COMTALDH1A1 | |
| SCHEMBL8041245 | 0.80 | MAPT (0.39) | COMTALDH1A1 | |
| SCHEMBL8037861 | 0.79 | PPIA (0.41) | TAS1R3TAS1R1TAS1R2TTRALDH1A1 | |
| SCHEMBL8037250 | 0.77 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL8025508 | 0.77 | ALDH1A1 (0.37) | COMTALDH1A1 | |
| SCHEMBL8040243 | 0.75 | PPIA (0.47) | ALDH1A1 | |
| SCHEMBL8035603 | 0.75 | RAB9A (0.40) | ALDH1A1 | |
| SCHEMBL8025492 | 0.74 | PPIA (0.49) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |