Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537762 | 0.83 | PPARG (0.48) | PPARGALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8037983 | 0.82 | MAPT (0.61) | ALDH1A1HPGDKMT2A | |
| SCHEMBL8034326 | 0.79 | PPARG (0.48) | PPARG | |
| SCHEMBL22004952 | 0.79 | PTGER4 (0.55) | ALDH1A1KDM4ELMNAHDAC1HDAC3 | |
| SCHEMBL4538730 | 0.78 | PPARG (0.57) | PPARGALDH1A1KDM4EHDAC1HDAC3 | |
| SCHEMBL8032490 | 0.78 | PPARG (0.55) | PPARGHDAC1HDAC3 | |
| SCHEMBL8034344 | 0.78 | PPARG (0.54) | PPARGHDAC1MEN1KMT2AHDAC3 | |
| SCHEMBL21925191 | 0.78 | LNPEP (0.53) | ALDH1A1KDM4EHPGDHSD17B10HDAC1 | |
| SCHEMBL8034302 | 0.78 | POLB (0.45) | PPARGALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL4537211 | 0.78 | KCNK3 (0.50) | PPARGHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |