Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19954207 | 0.82 | TSHR (0.52) | PYCR1CYP2C19CNR2ALDH1A1TSHR | |
| SCHEMBL13551804 | 0.81 | PYCR1 (0.47) | PYCR1CYP2C19CNR2ALDH1A1TSHR | |
| SCHEMBL19465823 | 0.79 | ALOX5 (0.37) | TSHR | |
| SCHEMBL18463851 | 0.75 | CRHBP (0.39) | PYCR1RIPK1 | |
| SCHEMBL11799987 | 0.72 | MMP13 (0.44) | PYCR1CYP2C19ALDH1A1 | |
| SCHEMBL32689849 | 0.71 | HRH3 (0.54) | PYCR1CYP2C19CNR2ALDH1A1TSHR | |
| SCHEMBL16312619 | 0.71 | PYCR1 (0.65) | PYCR1CYP2C19ALDH1A1TSHRIDO1 | |
| SCHEMBL12374 | 0.71 | HRH3 (0.67) | PYCR1CYP2C19ALDH1A1TSHRIDO1 | |
| SCHEMBL4402952 | 0.70 | CYP2C19 (0.52) | PYCR1CYP2C19CNR2ALDH1A1TSHR | |
| SCHEMBL15079442 | 0.70 | CYP2C19 (0.52) | PYCR1CYP2C19CNR2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099177-A1 | AMINO IMIDAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-13 | — | — | WO | disclosed |