Cyclohexylamine

Cyclohexylamine

SCHEMBL8041275

NC1CCCCC1.NCC(N)C(=O)O.O=Cc1ccc(Oc2ccccc2)cc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.40
NPY5R Q15761 1/20 0.40
PARP10 Q53GL7 1/20 0.40
PARP3 Q9Y6F1 1/20 0.40
PPARG P37231 2/20 0.39
PPARA Q07869 2/20 0.39
EPHX1 P07099 1/20 0.39
ALDH1A1 P00352 2/20 0.38
KIF11 P52732 2/20 0.38
FFAR1 O14842 1/20 0.37
METAP2 P50579 4/20 0.37
METAP1 P53582 2/20 0.37
KCNH2 Q12809 1/20 0.36
SCN3A Q9NY46 1/20 0.36
FNTA P49354 1/20 0.36
FNTB P49356 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexylamine SCHEMBL8041272 1.00 LTA4H (0.40) LTA4HNPY5RPARP10PARP3PPARG
Cyclohexylamine SCHEMBL8037294 0.91 EPOR (0.41) LTA4HNPY5RPPARGPPARAKCNH2
Cyclohexylamine SCHEMBL8037292 0.91 EPOR (0.41) LTA4HNPY5RPPARGPPARAKCNH2
Benzaldehyde SCHEMBL8035694 0.89 KIF11 (0.42) PPARGPPARAALDH1A1KIF11
Lysine SCHEMBL8035235 0.88 DPP8 (0.45) LTA4HNPY5RPARP10PARP3PPARG
Lysine SCHEMBL8035239 0.88 DPP8 (0.45) LTA4HNPY5RPARP10PARP3PPARG
Cyclohexylamine SCHEMBL7800175 0.87 PARP10 (0.44) NPY5RPARP10PARP3EPHX1ALDH1A1
Cyclohexylamine SCHEMBL8041427 0.87 GRIK1 (0.43) NPY5RPPARGPPARAKIF11FFAR1
Cyclohexylamine SCHEMBL8041423 0.87 GRIK1 (0.43) NPY5RPPARGPPARAKIF11FFAR1
Cycloheptanamine SCHEMBL7802529 0.85 PARP10 (0.45) PARP10PARP3EPHX1ALDH1A1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127381-A A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY LION BIOSCIENCE AG (DE) 2000-10-03 US disclosed