Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8037292 | 1.00 | EPOR (0.41) | EPORPKMMAOAMAOBPPARG | |
| Cyclohexylamine SCHEMBL8041427 | 0.93 | GRIK1 (0.43) | EPORPPARGPPARAGRIK1GRIK2 | |
| Cyclohexylamine SCHEMBL8041423 | 0.93 | GRIK1 (0.43) | EPORPPARGPPARAGRIK1GRIK2 | |
| Cyclohexylamine SCHEMBL8041275 | 0.91 | LTA4H (0.40) | PPARGPPARAKCNH2NPY5RLTA4H | |
| Cyclohexylamine SCHEMBL8041272 | 0.91 | LTA4H (0.40) | PPARGPPARAKCNH2NPY5RLTA4H | |
| Cyclohexylamine SCHEMBL8035834 | 0.90 | KMO (0.41) | PPARGPPARAGRIK1GRIK2HPGD | |
| Cyclohexylamine SCHEMBL8035833 | 0.90 | KMO (0.41) | PPARGPPARAGRIK1GRIK2HPGD | |
| Lysine SCHEMBL8025564 | 0.89 | DPP8 (0.43) | EPORPKMHPGDLTA4H | |
| Lysine SCHEMBL8025565 | 0.89 | DPP8 (0.43) | EPORPKMHPGDLTA4H | |
| Cyclohexylamine SCHEMBL7800890 | 0.89 | EPOR (0.47) | EPORPKMMAOAMAOBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |