Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8041414 | 1.00 | GRIK1 (0.45) | GRIK1GRIK2ALDH1A1KIF11KDM4E | |
| Cyclohexylamine SCHEMBL7802131 | 0.87 | ALDH1A1 (0.50) | GRIK1GRIK2ALDH1A1KDM4ESMN1; SMN2 | |
| 4-Hydroxybenzaldehyde SCHEMBL8037276 | 0.85 | ALDH5A1 (0.41) | GRIK1GRIK2ALDH1A1KIF11MEN1 | |
| 4-Hydroxybenzaldehyde SCHEMBL8037281 | 0.85 | ALDH5A1 (0.41) | GRIK1GRIK2ALDH1A1KIF11MEN1 | |
| Benzaldehyde SCHEMBL8035694 | 0.85 | KIF11 (0.42) | GRIK1GRIK2ALDH1A1KIF11MEN1 | |
| Cyclohexylamine SCHEMBL8037416 | 0.84 | ALDH1A1 (0.47) | GRIK1GRIK2ALDH1A1KIF11RAB9A | |
| Cyclohexylamine SCHEMBL8037697 | 0.84 | GRIK1 (0.41) | GRIK1GRIK2ALDH1A1KIF11SMN1; SMN2 | |
| Cyclohexylamine SCHEMBL8037511 | 0.84 | GRIK1 (0.42) | GRIK1GRIK2ALDH1A1KIF11MEN1 | |
| Cyclohexylamine SCHEMBL8037514 | 0.84 | GRIK1 (0.42) | GRIK1GRIK2ALDH1A1KIF11MEN1 | |
| Cyclohexylamine SCHEMBL8037696 | 0.84 | GRIK1 (0.41) | GRIK1GRIK2ALDH1A1KIF11SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |