Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 6/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8035833 | 1.00 | KMO (0.41) | KMOADAMTS5FAAHDRD2ADRA1A | |
| Cyclohexylamine SCHEMBL7802825 | 0.90 | KMO (0.44) | KMOADAMTS5FAAHNPC1GAA | |
| Lysine SCHEMBL8037515 | 0.90 | KMO (0.38) | KMOADAMTS5FAAHDRD2ADRA1A | |
| Lysine SCHEMBL8037512 | 0.90 | KMO (0.38) | KMOADAMTS5FAAHDRD2ADRA1A | |
| Cyclohexylamine SCHEMBL8037292 | 0.90 | EPOR (0.41) | HPGDKMT2APPARGPPARAGRIK1 | |
| Cyclohexylamine SCHEMBL8037294 | 0.90 | EPOR (0.41) | HPGDKMT2APPARGPPARAGRIK1 | |
| Cyclohexylamine SCHEMBL7792578 | 0.88 | ADAMTS5 (0.47) | KMOADAMTS5NPC1GAAMAPT | |
| Cyclohexylamine SCHEMBL8041427 | 0.87 | GRIK1 (0.43) | ADAMTS5NPC1RAB9AKMT2APPARG | |
| Cyclohexylamine SCHEMBL8041423 | 0.87 | GRIK1 (0.43) | ADAMTS5NPC1RAB9AKMT2APPARG | |
| Cyclohexylamine SCHEMBL8041275 | 0.84 | LTA4H (0.40) | MAPTPPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |