Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038199 | 0.93 | THRA (0.43) | TSHRALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL23581944 | 0.82 | KDM4E (0.39) | ALDH1A1KDM4ETDP1THRATHRB | |
| SCHEMBL1880444 | 0.81 | KDM4E (0.46) | TSHRALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL1561008 | 0.80 | ALDH1A1 (0.43) | TSHRALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL28654629 | 0.79 | NPC1 (0.39) | ALDH1A1KDM4EHPGDTDP1THRA | |
| SCHEMBL3053163 | 0.79 | THRB (0.44) | ALDH1A1TDP1THRATHRBGAA | |
| SCHEMBL5530462 | 0.78 | KMT2A (0.44) | ALDH1A1TDP1THRATHRBHSD17B10 | |
| SCHEMBL1249888 | 0.78 | KDM4E (0.38) | ALDH1A1KDM4EHPGDTHRATHRB | |
| SCHEMBL6458858 | 0.78 | ALDH1A1 (0.41) | TSHRALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL8038236 | 0.77 | AOC3 (0.40) | KDM4EHPGDSLC6A4MEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | disclosed |