Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 12/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5211360 | 0.96 | RIPK1 (0.37) | RIPK1OPRM1OPRD1OPRK1TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL6489279 | 0.89 | RIPK1 (0.35) | RIPK1OPRM1OPRD1OPRK1TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL7425564 | 0.89 | RIPK1 (0.36) | RIPK1OPRM1OPRD1OPRK1TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5629844 | 0.88 | OPRM1 (0.34) | RIPK1OPRM1OPRD1OPRK1TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL7433118 | 0.88 | RIPK1 (0.39) | RIPK1TPSAB1ROCK1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7430442 | 0.88 | RIPK1 (0.38) | RIPK1OPRM1OPRD1OPRK1ROCK1 | |
| Trifluoroacetic Acid SCHEMBL5211441 | 0.87 | RIPK1 (0.38) | RIPK1OPRM1OPRD1OPRK1TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL7421783 | 0.87 | OPRM1 (0.34) | RIPK1OPRM1OPRD1OPRK1TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5208180 | 0.87 | RIPK1 (0.42) | RIPK1ROCK1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5212450 | 0.87 | RIPK1 (0.39) | RIPK1OPRM1OPRD1OPRK1TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000077027-A2 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2000-12-21 | — | — | WO | disclosed |