Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214854 | 0.76 | ALDH1A1 (0.38) | HTR6ALDH1A1HSD17B10MEN1LMNA | |
| SCHEMBL29422894 | 0.73 | ALDH1A1 (0.35) | HTR6ALDH1A1HSD17B10MEN1LMNA | |
| SCHEMBL29569948 | 0.73 | ALDH1A1 (0.35) | HTR6ALDH1A1HSD17B10MEN1LMNA | |
| SCHEMBL30041234 | 0.73 | ALDH1A1 (0.35) | HTR6ALDH1A1HSD17B10MEN1LMNA | |
| SCHEMBL219752 | 0.73 | TSHR (0.36) | HTR6ALDH1A1HSD17B10MEN1LMNA | |
| SCHEMBL2926382 | 0.73 | ALDH1A1 (0.35) | HTR6ALDH1A1HSD17B10MEN1LMNA | |
| SCHEMBL2324920 | 0.73 | ALDH1A1 (0.35) | HTR6ALDH1A1HSD17B10MEN1LMNA | |
| SCHEMBL2926757 | 0.73 | ALDH1A1 (0.35) | HTR6ALDH1A1HSD17B10MEN1LMNA | |
| SCHEMBL5894113 | 0.73 | ALDH1A1 (0.35) | HTR6ALDH1A1HSD17B10MEN1LMNA | |
| SCHEMBL1941287 | 0.73 | ALDH1A1 (0.40) | HTR6ALDH1A1HSD17B10MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966703-A | Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | claimed |
| US-20230127304-A1 | NEW INHIBITORS FOR THE KEAP1-NRF2 PROTEIN-PROTEIN INTERACTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-04-27 | — | — | US | disclosed |
| US-20170306092-A1 | BENZOXAZINE COMPOUND | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2017-10-26 | — | — | US | disclosed |
| US-6158488-A | Rubber composition containing modified carbon black and article having component thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-12-12 | — | — | US | disclosed |
| EP-0992535-A1 | Rubber composition containing silanol modified carbon black | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-04-12 | — | — | EP | disclosed |
| US-4534908-A | Water-soluble disazo compounds and new bis-(aminophenoxy)-ethane compounds having fiber-reactive groups as the tetrazo components, and use of the disazo compounds as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127304-A1 | NEW INHIBITORS FOR THE KEAP1-NRF2 PROTEIN-PROTEIN INTERACTION | KEAP1, HMOX1, NFE2L2 | HTR6 4227/4885ALDH1A1 1402/4885HSD17B10 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.