Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535606 | 0.88 | ALDH1A1 (0.64) | ALDH1A1HDAC8MAPTKMT2AMEN1 | |
| SCHEMBL8033328 | 0.87 | ALDH1A1 (0.55) | ALDH1A1HDAC8MAPTKMT2AMEN1 | |
| SCHEMBL4538645 | 0.82 | MAPT (0.54) | ALDH1A1HDAC8MAPTKMT2AMEN1 | |
| SCHEMBL8037607 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HDAC8MAPTKMT2AMEN1 | |
| SCHEMBL4537985 | 0.78 | MAPT (0.62) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL15038578 | 0.78 | HDAC8 (0.49) | ALDH1A1HDAC8MAPTKMT2AMEN1 | |
| SCHEMBL4308882 | 0.77 | ABL1 (0.51) | ALDH1A1HDAC8MAPTKMT2AMEN1 | |
| SCHEMBL8033332 | 0.76 | MEN1 (0.54) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL11240016 | 0.76 | CA1 (0.75) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL29245006 | 0.76 | CA1 (0.75) | ALDH1A1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |