Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PPM1D | O15297 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033332 | 0.88 | MEN1 (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8041888 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL8033450 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ASSTR3LMNA | |
| SCHEMBL8038721 | 0.85 | MEN1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8039815 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ASMN1; SMN2SSTR3 | |
| SCHEMBL8033328 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL4539438 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8037607 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL4542148 | 0.79 | LMNA (0.53) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL28680863 | 0.76 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |