Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ILK | Q13418 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044591 | 0.82 | PKM (0.46) | PKMKMT2AHTTMAPTSMN1; SMN2 | |
| SCHEMBL8033856 | 0.82 | PKM (0.46) | PKMKMT2AHTTMAPTSMN1; SMN2 | |
| SCHEMBL8046347 | 0.81 | PDK1 (0.60) | KMT2AHTTMAPTSMN1; SMN2LMNA | |
| SCHEMBL8032955 | 0.80 | ALDH1A1 (0.49) | KMT2AHTTMAPTSMN1; SMN2LMNA | |
| SCHEMBL8043094 | 0.80 | ALDH1A1 (0.44) | PKMKMT2AHTTMAPTSMN1; SMN2 | |
| SCHEMBL8034241 | 0.78 | ALDH1A1 (0.50) | KMT2AHTTMAPTSMN1; SMN2LMNA | |
| SCHEMBL8042747 | 0.78 | PKM (0.42) | PKMKMT2AHTTMAPTSMN1; SMN2 | |
| SCHEMBL8044955 | 0.78 | USP2 (0.48) | PKMKMT2AHTTMAPTSMN1; SMN2 | |
| SCHEMBL8044433 | 0.78 | KMT2A (0.47) | PKMKMT2AHTTMAPTSMN1; SMN2 | |
| SCHEMBL8049026 | 0.77 | PKM (0.46) | PKMKMT2AHTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |