Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051920 | 0.87 | TSHR (0.51) | USP2ALDH1A1HSD17B10KDM4ENPC1 | |
| SCHEMBL8046372 | 0.86 | RAB9A (0.41) | USP2ALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL8044738 | 0.85 | CSNK1D (0.39) | USP2ALDH1A1HSD17B10KDM4ENPC1 | |
| SCHEMBL8042112 | 0.85 | CSNK1D (0.39) | USP2ALDH1A1HSD17B10KDM4ENPC1 | |
| SCHEMBL8044044 | 0.85 | KMT2A (0.45) | USP2ALDH1A1HSD17B10KDM4ENPC1 | |
| SCHEMBL8051273 | 0.85 | TSHR (0.42) | USP2ALDH1A1HSD17B10KDM4ENPC1 | |
| SCHEMBL8045522 | 0.85 | PKM (0.44) | ALDH1A1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL8046376 | 0.84 | SMN1; SMN2 (0.41) | USP2ALDH1A1HSD17B10KDM4ENPC1 | |
| SCHEMBL8042322 | 0.84 | ALDH1A1 (0.42) | USP2ALDH1A1HSD17B10KDM4ENPC1 | |
| SCHEMBL8051768 | 0.83 | PDK1 (0.51) | USP2ALDH1A1HSD17B10KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |