Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051659 | 0.85 | KMT2A (0.49) | HPGDRAB9ANPC1TSHRHTT | |
| SCHEMBL8042411 | 0.85 | KMT2A (0.39) | CPB1HPGDRAB9ANPC1TSHR | |
| SCHEMBL8044639 | 0.85 | HDAC6 (0.49) | USP2RAB9ANPC1TSHRALDH1A1 | |
| SCHEMBL8047063 | 0.83 | TSHR (0.51) | USP2HPGDTSHRHTTALDH1A1 | |
| SCHEMBL8047418 | 0.83 | KMT2A (0.38) | CPB1HPGDRAB9ANPC1TSHR | |
| SCHEMBL8042697 | 0.81 | ALDH1A1 (0.43) | HPGDRAB9ANPC1TSHRLMNA | |
| SCHEMBL8033984 | 0.79 | RAB9A (0.45) | CPB1USP2HPGDRAB9ANPC1 | |
| SCHEMBL8041830 | 0.79 | CPB1 (0.47) | CPB1USP2HPGDRAB9ANPC1 | |
| SCHEMBL8042509 | 0.79 | HSD17B10 (0.47) | USP2HPGDTSHRHTTALDH1A1 | |
| SCHEMBL8044326 | 0.78 | NPSR1 (0.47) | USP2HPGDTSHRHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |