Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044988 | 0.76 | KDM4E (0.58) | LMNA | |
| SCHEMBL8046043 | 0.74 | HTT (0.42) | LMNA | |
| SCHEMBL8041800 | 0.73 | HSD17B10 (0.34) | LMNA | |
| SCHEMBL8033591 | 0.71 | — | — | |
| SCHEMBL8042817 | 0.70 | ALDH1A1 (0.50) | LMNA | |
| SCHEMBL8047624 | 0.69 | GAA (0.40) | LMNA | |
| SCHEMBL8042707 | 0.68 | ALDH1A1 (0.46) | LMNA | |
| SCHEMBL8044820 | 0.67 | — | — | |
| SCHEMBL8043814 | 0.67 | NPC1 (0.38) | LMNA | |
| SCHEMBL8045769 | 0.65 | ALDH1A1 (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |