Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050969 | 0.89 | KMT2A (0.39) | ALDH1A1SMN1; SMN2GAAKMT2ALMNA | |
| SCHEMBL8042957 | 0.86 | HTT (0.41) | ALDH1A1POLBGAAKMT2ALMNA | |
| SCHEMBL8045327 | 0.83 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2RCE1POLBGAA | |
| SCHEMBL8042600 | 0.81 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2RCE1KMT2ANPC1 | |
| SCHEMBL8712546 | 0.80 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KMT2ALMNACYP2C19 | |
| SCHEMBL8042403 | 0.80 | DCUN1D1 (0.38) | KMT2ALMNA | |
| SCHEMBL8046043 | 0.80 | HTT (0.42) | ALDH1A1SMN1; SMN2POLBGAAKMT2A | |
| SCHEMBL8044545 | 0.79 | ALDH1A1 (0.45) | ALDH1A1GAAKMT2ALMNARAB9A | |
| SCHEMBL8033923 | 0.77 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2POLBGAAKMT2A | |
| SCHEMBL8033637 | 0.77 | LMNA (0.32) | ALDH1A1KMT2ALMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |