Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043654 | 0.85 | TSHR (0.52) | HDAC6MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8043803 | 0.83 | HDAC6 (0.41) | HDAC6POLBSMN1; SMN2NPSR1NPC1 | |
| SCHEMBL8052238 | 0.83 | POLB (0.45) | HDAC6POLBMEN1KMT2AATM | |
| SCHEMBL8042586 | 0.82 | RPA1 (0.47) | HDAC6MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8045350 | 0.81 | SMN1; SMN2 (0.39) | HDAC6MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8042913 | 0.81 | ALDH1A1 (0.44) | HDAC6POLBSMN1; SMN2NPSR1ADORA3 | |
| SCHEMBL8046929 | 0.80 | TSHR (0.52) | HDAC6MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8032459 | 0.80 | HSD17B10 (0.49) | HDAC6MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8049866 | 0.80 | PKM (0.45) | HDAC6POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8045038 | 0.79 | TSHR (0.47) | HDAC6MEN1KMT2ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |