Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032967 | 0.90 | RAB9A (0.48) | RAB9AMAPTNPC1LMNAALDH1A1 | |
| SCHEMBL8048236 | 0.89 | MAPT (0.44) | RAB9AMAPTNPC1LMNAALDH1A1 | |
| SCHEMBL8032807 | 0.87 | MEN1 (0.45) | RAB9AMAPTNPC1LMNAALDH1A1 | |
| SCHEMBL8033209 | 0.86 | HTR1A (0.49) | RAB9AMAPTNPC1LMNAALDH1A1 | |
| SCHEMBL8048093 | 0.86 | RAB9A (0.43) | RAB9AMAPTNPC1LMNAALDH1A1 | |
| SCHEMBL8048496 | 0.85 | MEN1 (0.43) | RAB9AMAPTNPC1LMNAALDH1A1 | |
| SCHEMBL8047850 | 0.83 | MEN1 (0.44) | RAB9AMAPTNPC1LMNAALDH1A1 | |
| SCHEMBL8041816 | 0.82 | RAB9A (0.47) | RAB9AMAPTNPC1LMNAALDH1A1 | |
| SCHEMBL8045211 | 0.82 | KMT2A (0.48) | RAB9AMAPTNPC1LMNAALDH1A1 | |
| SCHEMBL8042084 | 0.82 | ALDH1A1 (0.49) | RAB9AMAPTNPC1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |