Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | PLAU | P00749 | 3/20 | 0.44 |
| ▸ | C1S | P09871 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032700 | 0.85 | HTR1A (0.49) | RAB9ANPC1PLAUC1SLMNA | |
| SCHEMBL8042056 | 0.84 | FBP1 (0.51) | RAB9ANPC1PLAUC1SLMNA | |
| SCHEMBL8032730 | 0.82 | RAB9A (0.43) | RAB9ANPC1PLAUC1SLMNA | |
| SCHEMBL8041954 | 0.82 | RAB9A (0.43) | RAB9ANPC1PLAUC1SLMNA | |
| SCHEMBL8042990 | 0.82 | RAB9A (0.47) | RAB9ANPC1PLAUC1SLMNA | |
| SCHEMBL8032967 | 0.80 | RAB9A (0.48) | RAB9ANPC1PLAUC1SLMNA | |
| SCHEMBL8043773 | 0.80 | KMT2A (0.47) | RAB9ANPC1PLAULMNAKMT2A | |
| SCHEMBL8051857 | 0.80 | ALOX5 (0.44) | RAB9ANPC1LMNAALDH1A1MAPT | |
| SCHEMBL8032807 | 0.80 | MEN1 (0.45) | RAB9ANPC1PLAUC1SLMNA | |
| SCHEMBL8048093 | 0.79 | RAB9A (0.43) | RAB9ANPC1PLAUC1SLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |