SCHEMBL804308

SCHEMBL804308

CC(C)(OC=O)Oc1ccc(NC(=O)Cc2ccccc2CC(=O)Nc2ccc(OC(C)(C)C(=O)O)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.45
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPT P10636 2/20 0.44
ALDH1A1 P00352 1/20 0.44
NPC1 O15118 1/20 0.43
HPGD P15428 1/20 0.43
PPARA Q07869 10/20 0.42
PPARG P37231 6/20 0.42
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP2C9 P11712 1/20 0.41
ADRB3 P13945 3/20 0.41
MEN1 O00255 1/20 0.41
CYP3A4 P08684 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16743459 0.86 KMT2A (0.50) GAARAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL804326 0.83 PPARA (0.49) RAB9ASMN1; SMN2MAPTALDH1A1NPC1
SCHEMBL16302959 0.83 PPARA (0.49) RAB9ASMN1; SMN2MAPTALDH1A1NPC1
SCHEMBL12202895 0.82 PPARG (0.53) MAPTPPARAPPARGCYP1A2CYP2D6
SCHEMBL806019 0.80 RAB9A (0.68) GAARAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL804816 0.80 TRPV1 (0.46) RAB9ASMN1; SMN2MAPTALDH1A1NPC1
SCHEMBL16743450 0.79 MTNR1A (0.46) GAARAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL12202894 0.79 PPARA (0.52) MAPTPPARAPPARGCYP1A2CYP2D6
SCHEMBL6557488 0.78 RAB9A (0.59) GAARAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL16302944 0.77 PPARA (0.49) PPARAPPARGADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040553-B2 Phenoxyisobutyric acid compounds and method of synthesis Cell Viable Corporation (US) 2015-05-26 US disclosed
US-20140350045-A1 PHENOXYISOBUTYRIC ACID COMPOUNDS AND METHOD OF SYNTHESIS LALEZARI IRAJ (US) 2014-11-27 US disclosed
US-20120071502-A1 Novel phenoxyisobutyric acid compounds and methods for synthesis Cell Viable Corporation (US) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140350045-A1 PHENOXYISOBUTYRIC ACID COMPOUNDS AND METHOD OF SYNTHESIS AGER, BPGM, PDXK GAA 94/4885RAB9A 2312/4885SMN1; SMN2 3746/4885
US-20120071502-A1 Novel phenoxyisobutyric acid compounds and methods for synthesis AGER, BPGM, PDXK GAA 107/4885RAB9A 2087/4885SMN1; SMN2 3831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.