Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026997 | 0.79 | KMT2A (0.44) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL16870308 | 0.67 | MEN1 (0.37) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL1699532 | 0.66 | ACHE (0.63) | KDM4EALDH1A1HPGDACHELMNA | |
| SCHEMBL16870309 | 0.64 | MAOA (0.41) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL13626344 | 0.64 | TUBB4A (0.40) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL14722618 | 0.63 | KDM4E (0.39) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL14722619 | 0.63 | KDM4E (0.39) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL22829411 | 0.63 | ACHE (0.44) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL30815971 | 0.63 | ACHE (0.44) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL6113045 | 0.62 | KDM4E (0.64) | KMT2AMEN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124498-A | Hydroxynaphthoic acids and derivatives | UNIVERSITY OF NEW MEXICO (US) | 2000-09-26 | — | — | US | disclosed |