Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043165 | 0.79 | KMT2A (0.40) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL16870308 | 0.72 | MEN1 (0.37) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL1699532 | 0.71 | ACHE (0.63) | KDM4EALDH1A1HPGDACHEBRD4 | |
| SCHEMBL7998453 | 0.70 | KDM4E (0.54) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL6113045 | 0.70 | KDM4E (0.64) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL7172176 | 0.69 | ALDH1A1 (0.49) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL16870309 | 0.69 | MAOA (0.41) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL13626344 | 0.69 | TUBB4A (0.40) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL11708730 | 0.68 | BRD4 (0.46) | KDM4EALDH1A1HPGDBRD4GAA | |
| SCHEMBL4132763 | 0.68 | KDM4E (0.51) | KMT2AMEN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124498-A | Hydroxynaphthoic acids and derivatives | UNIVERSITY OF NEW MEXICO (US) | 2000-09-26 | — | — | US | disclosed |