SCHEMBL804329

SCHEMBL804329

CC(C)(OC=O)Oc1ccc(NCc2ccc3cc(C(=O)Nc4ccc(OC(C)(C)C(=O)O)cc4)ccc3c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 4/20 0.46
PLAU P00749 3/20 0.43
F2 P00734 1/20 0.43
PLG P00747 1/20 0.43
PLAT P00750 1/20 0.43
KLKB1 P03952 1/20 0.43
PRSS1 P07477 1/20 0.43
NR1H4 Q96RI1 1/20 0.42
PPARA Q07869 9/20 0.42
NPC1 O15118 1/20 0.41
CASP3 P42574 1/20 0.41
RAB9A P51151 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
PPARG P37231 4/20 0.41
PPARD Q03181 2/20 0.41
CTNNB1 P35222 1/20 0.41
TCF7L2 Q9NQB0 1/20 0.41
ALDH1A1 P00352 1/20 0.40
FABP2 P12104 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL805970 0.92 DGAT1 (0.53) DGAT1PLAUF2PLGPLAT
SCHEMBL12202894 0.85 PPARA (0.52) PPARAPPARGPPARD
SCHEMBL804816 0.84 TRPV1 (0.46) DGAT1PPARANPC1CASP3RAB9A
SCHEMBL16265137 0.83 TRPV1 (0.43) DGAT1PPARANPC1RAB9APPARG
SCHEMBL16302944 0.83 PPARA (0.49) PPARAPPARGPPARD
SCHEMBL804724 0.81 PGR (0.50) NR1H4PPARANPC1RAB9APPARG
SCHEMBL16302945 0.79 PPARA (0.45) PPARAPPARGPPARD
SCHEMBL14976928 0.77 NPC1 (0.67) DGAT1PLAUNR1H4NPC1CASP3
SCHEMBL16743653 0.76 NPC1 (0.52) DGAT1PLAUPLGPLATPPARA
SCHEMBL16302959 0.76 PPARA (0.49) PPARANPC1RAB9APPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040553-B2 Phenoxyisobutyric acid compounds and method of synthesis Cell Viable Corporation (US) 2015-05-26 US disclosed
US-20140350045-A1 PHENOXYISOBUTYRIC ACID COMPOUNDS AND METHOD OF SYNTHESIS LALEZARI IRAJ (US) 2014-11-27 US disclosed
US-20120071502-A1 Novel phenoxyisobutyric acid compounds and methods for synthesis Cell Viable Corporation (US) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140350045-A1 PHENOXYISOBUTYRIC ACID COMPOUNDS AND METHOD OF SYNTHESIS AGER, BPGM, PDXK DGAT1 1602/4885PLAU 1633/4885F2 1520/4885
US-20120071502-A1 Novel phenoxyisobutyric acid compounds and methods for synthesis AGER, BPGM, PDXK DGAT1 1455/4885PLAU 1949/4885F2 2891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.