SCHEMBL8043313

SCHEMBL8043313

CCOC([SiH3])C(OCC)(OCC)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.36
KCNN4 O15554 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.32
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
KIF11 P52732 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
ALDH1A1 P00352 2/20 0.31
TSHR P16473 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574402 0.91
SCHEMBL574685 0.88
SCHEMBL329528 0.86 KMT2A (0.30)
SCHEMBL307119 0.84 L3MBTL1 (0.33) L3MBTL1
SCHEMBL5586177 0.79 L3MBTL1 (0.31) L3MBTL1
SCHEMBL329707 0.77 SMN1; SMN2 (0.38) L3MBTL1LMNAALDH1A1
SCHEMBL10798685 0.76 LMNA (0.40) KCNN4LMNAEDNRBEDNRACYP3A4
SCHEMBL7686100 0.73 LMNA (0.42) KCNN4LMNAEDNRBEDNRAKIF11
SCHEMBL10660143 0.71 LMNA (0.42) LMNAMAPK1EDNRBEDNRACYP3A4
SCHEMBL7922550 0.69 ALDH1A1 (0.38) L3MBTL1KCNN4LMNAMAPK1EDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0991698-A1 SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME CK WITCO CORPORATION (US) 2000-04-12 EP disclosed
WO-1999054386-A1 SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME WITCO CORPORATION (US) 1999-10-28 WO disclosed