⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043313 | 0.88 | L3MBTL1 (0.36) | — | |
| SCHEMBL574402 | 0.85 | — | — | |
| SCHEMBL329528 | 0.81 | KMT2A (0.30) | — | |
| SCHEMBL307119 | 0.79 | L3MBTL1 (0.33) | — | |
| SCHEMBL5586177 | 0.75 | L3MBTL1 (0.31) | — | |
| SCHEMBL329707 | 0.72 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL574709 | 0.67 | PGK1 (0.31) | — | |
| SCHEMBL4119769 | 0.66 | THRB (0.38) | — | |
| SCHEMBL10798685 | 0.63 | LMNA (0.40) | — | |
| SCHEMBL15736661 | 0.61 | L3MBTL1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190015815-A1 | SUPERFICIALLY POROUS MATERIALS COMPRISING A COATED CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | WATERS TECHNOLOGIES CORPORATION | 2019-01-17 | — | — | US | claimed |
| EP-3426388-A1 | SUPERFICIALLY POROUS MATERIALS COMPRISING A COATED CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | Waters Technologies Corporation (US) | 2019-01-16 | — | — | EP | claimed |
| EP-2598440-A2 | SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS HYBRID CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | Waters Technologies Corporation (US) | 2013-06-05 | — | — | EP | claimed |
| EP-2598441-A1 | SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | Waters Technologies Corporation (US) | 2013-06-05 | — | — | EP | claimed |
| WO-2012018598-A1 | SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | WATERS TECHNOLOGIES CORPORATION (US) | 2012-02-09 | — | — | WO | claimed |
| WO-2012018596-A2 | SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS HYBRID CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | WATERS TECHNOLOGIES CORPORATION (US) | 2012-02-09 | — | — | WO | claimed |
| US-12623205-B2 | Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution | WATERS TECHNOLOGIES CORPORATION (US) | 2026-05-12 | — | — | US | disclosed |
| US-12611617-B2 | Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography | WATERS TECHNOLOGIES CORPORATION (US) | 2026-04-28 | — | — | US | disclosed |
| EP-3834927-B1 | METHOD FOR PREPARING A SUPERFICIALLY POROUS MATERIAL | WATERS TECHNOLOGIES CORP (US) | 2026-03-25 | — | — | EP | disclosed |
| US-20250387778-A1 | SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | WATERS TECHNOLOGIES CORPORATION (US) | 2025-12-25 | — | — | US | disclosed |
| EP-3426390-B1 | POROUS MATERIALS WITH CONTROLLED POROSITY AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | WATERS TECHNOLOGIES CORP (US) | 2025-12-17 | — | — | EP | disclosed |
| EP-4353682-B1 | SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS HYBRID CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION, USEFUL FOR CHROMATOGRAPHIC SEPARATIONS | WATERS TECHNOLOGIES CORP (US) | 2025-11-12 | — | — | EP | disclosed |
| US-12427502-B2 | Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations | WATERS TECHNOLOGIES CORPORATION (US) | 2025-09-30 | — | — | US | disclosed |
| WO-2014201033-A1 | CHROMATOGRAPHIC COLUMNS AND SEPARATION DEVICES COMPRISING A SUPERFICIALLY POROUS MATERIAL; AND USE THEREOF FOR SUPERCRITICAL FLUID CHROMATOGRAPHY AND OTHER CHROMATOGRAPHY | WATERS TECHNOLOGIES CORPORATION (US) | 2014-12-18 | — | — | WO | disclosed |
| US-20130206665-A1 | SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS HYBRID CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | WATERS TECHNOLOGIES CORPORATION (US) | 2013-08-15 | — | — | US | disclosed |
| EP-2598441-A1 | SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | Waters Technologies Corporation (US) | 2013-06-05 | — | — | EP | disclosed |
| EP-2598440-A2 | SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS HYBRID CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | Waters Technologies Corporation (US) | 2013-06-05 | — | — | EP | disclosed |
| US-20130112605-A1 | SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | WATERS TECHNOLOGIES CORPORATION (US) | 2013-05-09 | — | — | US | disclosed |
| WO-2012018598-A1 | SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | WATERS TECHNOLOGIES CORPORATION (US) | 2012-02-09 | — | — | WO | disclosed |
| WO-2012018596-A2 | SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS HYBRID CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | WATERS TECHNOLOGIES CORPORATION (US) | 2012-02-09 | — | — | WO | disclosed |