Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 4/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048057 | 0.76 | RAB9A (0.39) | EGLN1RAB9APOLBSMN1; SMN2LMNA | |
| SCHEMBL8043319 | 0.73 | KDM4E (0.53) | FBP1PDK1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL8043572 | 0.71 | EGLN1 (0.38) | EGLN1RAB9APOLBSMN1; SMN2NPC1 | |
| SCHEMBL7114230 | 0.71 | FBP1 (0.70) | FBP1PDK1HTR7TSHRFLT3 | |
| SCHEMBL8033034 | 0.70 | FBP1 (0.47) | FBP1PDK1HTR7SMN1; SMN2FLT3 | |
| SCHEMBL8050307 | 0.68 | HTR1A (0.47) | EGLN1RAB9AHTR7SMN1; SMN2NPC1 | |
| SCHEMBL8043078 | 0.67 | FBP1 (0.47) | FBP1PDK1RAB9AHTR7NPC1 | |
| SCHEMBL8048521 | 0.67 | POLB (0.36) | EGLN1RAB9APOLBSMN1; SMN2LMNA | |
| SCHEMBL8045613 | 0.66 | RAB9A (0.44) | RAB9APOLBSMN1; SMN2NPC1LMNA | |
| SCHEMBL17274031 | 0.66 | FBP1 (0.45) | FBP1PDK1HTR7FLT3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |