Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043773 | 0.88 | KMT2A (0.47) | KDM4ERAB9ASMN1; SMN2LMNAALOX5 | |
| SCHEMBL8050637 | 0.80 | HDAC6 (0.49) | KDM4ERAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8043837 | 0.76 | KDM4E (0.40) | KDM4ERAB9ASMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL8044404 | 0.76 | ATM (0.44) | KDM4ERAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL10715489 | 0.76 | RAB9A (0.67) | KDM4ERAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8042056 | 0.75 | FBP1 (0.51) | KDM4ERAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8051082 | 0.74 | TSHR (0.55) | KDM4ERAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8041816 | 0.74 | RAB9A (0.47) | KDM4ERAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8042588 | 0.74 | KDM4E (0.46) | KDM4ERAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8032807 | 0.73 | MEN1 (0.45) | KDM4ERAB9ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |