Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526712 | 0.84 | TLR8 (0.42) | TLR8CNR2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8832486 | 0.83 | BCHE (0.33) | BCHE | |
| SCHEMBL8059204 | 0.81 | ACP3 (0.33) | BCHEALDH1A1MAPTSIGMAR1SLC6A4 | |
| SCHEMBL8056403 | 0.79 | ACP3 (0.31) | BCHEALDH1A1SLC18A2 | |
| SCHEMBL8043515 | 0.78 | ALDH1A1 (0.33) | ALDH1A1MAPTSIGMAR1GAA | |
| SCHEMBL8059198 | 0.78 | TLR8 (0.35) | TLR8CNR2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8056040 | 0.77 | ACP3 (0.35) | ALDH1A1 | |
| SCHEMBL8055032 | 0.77 | TLR8 (0.34) | TLR8CNR2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8059192 | 0.75 | ALDH1A1 (0.31) | ALDH1A1MAPT | |
| SCHEMBL8832750 | 0.74 | DRD2 (0.31) | ALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704449-B1 | Process for the preparation of diphosphanes | CELANESE CHEM EUROPE GMBH (DE) | 2000-05-24 | — | — | EP | disclosed |
| US-5696296-A | Diphosphines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| EP-0704449-A1 | Diphosphanes and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-03 | — | — | EP | disclosed |