Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576417 | 0.88 | NOTUM (0.34) | KDM4EHSD17B10ALDH1A1LMNAMAPK1 | |
| SCHEMBL8575409 | 0.84 | KDM4E (0.39) | KDM4EHSD17B10ALDH1A1LMNAMAPK1 | |
| SCHEMBL8059191 | 0.81 | SLC9A1 (0.42) | KDM4EHSD17B10ALDH1A1LMNAMAPK1 | |
| SCHEMBL8059253 | 0.81 | SLC9A1 (0.53) | — | |
| SCHEMBL8603912 | 0.80 | CA12 (0.49) | KDM4EHSD17B10ALDH1A1LMNAKMT2A | |
| SCHEMBL8576497 | 0.79 | KDM4E (0.35) | KDM4EHSD17B10ALDH1A1LMNAMAPK1 | |
| SCHEMBL8574141 | 0.78 | KDM4E (0.49) | KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8571645 | 0.77 | XDH (0.35) | KDM4EHSD17B10ALDH1A1LMNAMAPK1 | |
| SCHEMBL8055935 | 0.76 | GABRP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7768700 | 0.76 | CISD1 (0.47) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704431-B1 | Ortho-substituted benzoic acid derivatives | MERCK PATENT GMBH (DE) | 2000-05-24 | — | — | EP | disclosed |
| US-5849796-A | Ortho-substituted benzoil acid derivatives | MERCK PATENT GELSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0704431-A2 | Ortho-substituted benzoic acid derivatives | MERCK PATENT GmbH (DE) | 1996-04-03 | — | — | EP | disclosed |