Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575409 | 0.83 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8578521 | 0.81 | SLC9A1 (0.52) | — | |
| SCHEMBL7797968 | 0.81 | KDM4E (0.65) | KDM4ENPSR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8059191 | 0.80 | SLC9A1 (0.42) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8603912 | 0.79 | CA12 (0.49) | KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL7801323 | 0.78 | KDM4E (0.54) | KDM4ENPSR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10721823 | 0.78 | LCK (0.59) | KDM4ENPSR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8902619 | 0.78 | ALDH1A1 (0.50) | KDM4ENPSR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8576497 | 0.78 | KDM4E (0.35) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8043633 | 0.78 | GABRP (0.36) | KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849796-A | Ortho-substituted benzoil acid derivatives | MERCK PATENT GELSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0704431-A2 | Ortho-substituted benzoic acid derivatives | MERCK PATENT GmbH (DE) | 1996-04-03 | — | — | EP | disclosed |