Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576497 | 0.91 | KDM4E (0.35) | KDM4EHSD17B10LMNAALDH1A1MAPK1 | |
| SCHEMBL8059191 | 0.87 | SLC9A1 (0.42) | KDM4EHSD17B10LMNAALDH1A1MAPK1 | |
| SCHEMBL8576432 | 0.87 | ALDH1A1 (0.39) | KDM4EHSD17B10LMNAALDH1A1MAPK1 | |
| SCHEMBL8603912 | 0.85 | CA12 (0.49) | KDM4EHSD17B10LMNAALDH1A1CA12 | |
| SCHEMBL8043633 | 0.84 | GABRP (0.36) | KDM4EHSD17B10LMNAALDH1A1MAPK1 | |
| SCHEMBL8572717 | 0.83 | KDM4E (0.35) | KDM4EHSD17B10LMNAALDH1A1MAPK1 | |
| SCHEMBL8574141 | 0.83 | KDM4E (0.49) | KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8576417 | 0.82 | NOTUM (0.34) | KDM4EHSD17B10LMNAALDH1A1MAPK1 | |
| SCHEMBL8571645 | 0.82 | XDH (0.35) | KDM4EHSD17B10LMNAALDH1A1MAPK1 | |
| SCHEMBL8574451 | 0.81 | ABCC9 (0.37) | KDM4EHSD17B10NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849796-A | Ortho-substituted benzoil acid derivatives | MERCK PATENT GELSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0704431-A2 | Ortho-substituted benzoic acid derivatives | MERCK PATENT GmbH (DE) | 1996-04-03 | — | — | EP | disclosed |