Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043462 | 0.90 | RAB9A (0.47) | RAB9AALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL8042084 | 0.88 | ALDH1A1 (0.49) | RAB9AALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL8044700 | 0.83 | RAB9A (0.48) | RAB9AALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL8051288 | 0.83 | RAB9A (0.46) | RAB9AALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL8044267 | 0.83 | PARP1 (0.49) | RAB9AALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL8046099 | 0.81 | RAB9A (0.46) | RAB9AALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL8033209 | 0.81 | HTR1A (0.49) | RAB9AALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL8046645 | 0.81 | ALDH1A1 (0.39) | RAB9AALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL8048154 | 0.80 | ALDH1A1 (0.48) | RAB9AALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL8047850 | 0.80 | MEN1 (0.44) | RAB9AALDH1A1LMNAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |