Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 9/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038016 | 0.80 | HTT (0.46) | FBP1PDK1NPSR1ALDH1A1TSHR | |
| SCHEMBL8032325 | 0.76 | SMN1; SMN2 (0.36) | NPSR1ALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL8042471 | 0.76 | ALDH1A1 (0.47) | FBP1PDK1HTR7NPSR1KDM1A | |
| SCHEMBL8048086 | 0.76 | FBP1 (0.39) | FBP1PDK1HTR7FDPSNPSR1 | |
| SCHEMBL8044697 | 0.74 | HSD17B10 (0.43) | FBP1NPSR1ALDH1A1TSHRUSP2 | |
| SCHEMBL8045872 | 0.74 | FBP1 (0.40) | FBP1PDK1HTR7FDPSNPSR1 | |
| SCHEMBL8051237 | 0.74 | SMN1; SMN2 (0.30) | TSHRUSP2SMN1; SMN2 | |
| SCHEMBL8045352 | 0.74 | ALOX15 (0.41) | FBP1PDK1HTR7NPSR1ALDH1A1 | |
| SCHEMBL8043030 | 0.71 | HTT (0.42) | FBP1PDK1NPSR1ALDH1A1TSHR | |
| SCHEMBL8032540 | 0.71 | ALDH1A1 (0.53) | NPSR1ALDH1A1TSHRUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |