Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043030 | 0.92 | HTT (0.42) | ALOX15FBP1KMT2ALMNANPSR1 | |
| SCHEMBL8042471 | 0.88 | ALDH1A1 (0.47) | FBP1KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL8710280 | 0.83 | CYP2C9 (0.44) | ALOX15FBP1KMT2ALMNAHSD17B10 | |
| SCHEMBL8045829 | 0.83 | HTR7 (0.47) | KMT2ALMNANPSR1HTR7 | |
| SCHEMBL8038016 | 0.80 | HTT (0.46) | ALOX15FBP1KMT2ALMNAHSD17B10 | |
| SCHEMBL8032420 | 0.80 | ALDH1A1 (0.39) | KMT2ALMNAHSD17B10NPSR1ALDH1A1 | |
| SCHEMBL8044130 | 0.79 | NPSR1 (0.33) | ALOX15FBP1KMT2ALMNAHSD17B10 | |
| SCHEMBL8046169 | 0.78 | KDM4C (0.39) | ALOX15FBP1KMT2ALMNAHSD17B10 | |
| SCHEMBL8044019 | 0.77 | KMT2A (0.40) | ALOX15KMT2ALMNAHSD17B10NPSR1 | |
| SCHEMBL8051547 | 0.77 | KMT2A (0.48) | KMT2ALMNAALDH1A1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |