Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | FBP1 | P09467 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045352 | 0.88 | ALOX15 (0.41) | ALDH1A1FBP1PDK1NPC1RAB9A | |
| SCHEMBL8043030 | 0.86 | HTT (0.42) | ALDH1A1FBP1PDK1POLBNPSR1 | |
| SCHEMBL8046169 | 0.80 | KDM4C (0.39) | ALDH1A1FBP1L3MBTL1PDK1NPC1 | |
| SCHEMBL8045829 | 0.80 | HTR7 (0.47) | HTR7NPSR1KMT2ALMNAKDM1A | |
| SCHEMBL8710280 | 0.80 | CYP2C9 (0.44) | ALDH1A1FBP1PDK1RAB9AHTR7 | |
| SCHEMBL8038016 | 0.80 | HTT (0.46) | ALDH1A1FBP1L3MBTL1PDK1RAB9A | |
| SCHEMBL8051547 | 0.79 | KMT2A (0.48) | ALDH1A1RAB9AGAAHTTKMT2A | |
| SCHEMBL8051539 | 0.78 | L3MBTL1 (0.40) | ALDH1A1L3MBTL1NPSR1GAAHTT | |
| SCHEMBL8032420 | 0.77 | ALDH1A1 (0.39) | ALDH1A1NPC1RAB9APOLBNPSR1 | |
| SCHEMBL8044130 | 0.76 | NPSR1 (0.33) | FBP1RAB9ANPSR1TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |