Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KIF5B | P33176 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95212 | 0.84 | SIRT2 (0.41) | NNMTPDE10ASIRT2SIRT1KDM4E | |
| SCHEMBL29378197 | 0.84 | SIRT2 (0.41) | NNMTPDE10ASIRT2SIRT1KDM4E | |
| Resorcinol SCHEMBL8056965 | 0.84 | HSD17B1 (0.41) | NNMTRETKIF5BMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL3391003 | 0.83 | SIRT2 (0.40) | NNMTPDE10ASIRT2SIRT1KDM4E | |
| Hydrochloric Acid SCHEMBL31409347 | 0.83 | SIRT2 (0.40) | NNMTPDE10ASIRT2SIRT1KDM4E | |
| Hydrochloric Acid SCHEMBL4602018 | 0.83 | SIRT2 (0.40) | NNMTPDE10ASIRT2SIRT1KDM4E | |
| Hydrochloric Acid SCHEMBL22612465 | 0.81 | SIRT2 (0.39) | NNMTPDE10ASIRT2SIRT1KDM4E | |
| Orcinol SCHEMBL6424543 | 0.81 | NNMT (0.36) | NNMTPDE10ARETKIF5BSIRT2 | |
| SCHEMBL8056266 | 0.80 | CASP1 (0.50) | NNMTPDE10ARETKIF5BSIRT2 | |
| Sulfuric Acid SCHEMBL8448369 | 0.79 | NNMT (0.38) | NNMTPDE10AMTNR1AMTNR1BSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001734-A1 | DYES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006016-A1 | DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-02-11 | — | — | WO | disclosed |