Orcinol

Orcinol

SCHEMBL6424543

CNc1nc(OC)ccc1N.Cc1cc(O)cc(O)c1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NNMT P40261 1/20 0.36
ALDH1A1 P00352 4/20 0.34
PDE10A Q9Y233 2/20 0.34
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
PABPC1 P11940 1/20 0.33
RET P07949 1/20 0.33
KIF5B P33176 1/20 0.33
KDR P35968 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
CYP1A2 P05177 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
PIK3CA P42336 3/20 0.32
MTOR P42345 1/20 0.32
ACVR2A P27037 1/20 0.32
TGFBR1 P36897 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resorcinol SCHEMBL8056965 0.88 HSD17B1 (0.41) NNMTALDH1A1KMT2AMEN1RET
SCHEMBL29378197 0.86 SIRT2 (0.41) NNMTALDH1A1PDE10AKMT2ASIRT2
SCHEMBL95212 0.86 SIRT2 (0.41) NNMTALDH1A1PDE10AKMT2ASIRT2
SCHEMBL3245424 0.86 ALDH1A1 (0.41) NNMTALDH1A1PDE10AKMT2ARET
Hydrochloric Acid SCHEMBL3391003 0.84 SIRT2 (0.40) NNMTALDH1A1PDE10AKMT2ASIRT2
Hydrochloric Acid SCHEMBL31409347 0.84 SIRT2 (0.40) NNMTALDH1A1PDE10AKMT2ASIRT2
Hydrochloric Acid SCHEMBL4602018 0.84 SIRT2 (0.40) NNMTALDH1A1PDE10AKMT2ASIRT2
Hydrochloric Acid SCHEMBL22612465 0.82 SIRT2 (0.39) NNMTALDH1A1PDE10AKMT2ASIRT2
SCHEMBL8043904 0.81 NNMT (0.35) NNMTALDH1A1PDE10ARETKIF5B
SCHEMBL8056266 0.81 CASP1 (0.50) NNMTALDH1A1PDE10AKMT2ARET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6863698-B1 Agent for dyeing keratin containing fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-03-08 US disclosed
EP-1001734-A1 DYES Henkel Kommanditgesellschaft auf Aktien (DE) 2000-05-24 EP disclosed
WO-1999006016-A1 DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-02-11 WO disclosed