Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032728 | 0.89 | ALDH1A1 (0.37) | ALDH1A1HTTTSHRPKMLMNA | |
| SCHEMBL8044545 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HTTTSHRPKMLMNA | |
| SCHEMBL8047501 | 0.84 | L3MBTL1 (0.37) | ALDH1A1HTTTSHRLMNAMAPT | |
| SCHEMBL8043561 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HTTTSHRPKMLMNA | |
| SCHEMBL8045327 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HTTLMNARAB9AMAPT | |
| SCHEMBL8052246 | 0.80 | KMT2A (0.36) | ALDH1A1HTTLMNAMAPTNPSR1 | |
| SCHEMBL8046340 | 0.80 | KMT2A (0.34) | ALDH1A1HTTRAB9AHPGDMAPT | |
| SCHEMBL8033854 | 0.78 | ALDH1A1 (0.40) | ALDH1A1HTTTSHRPKMLMNA | |
| SCHEMBL8032337 | 0.78 | HTT (0.39) | ALDH1A1HTTTSHRPKMLMNA | |
| SCHEMBL8033664 | 0.78 | RAB9A (0.39) | ALDH1A1HTTTSHRLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |