Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044008 | 0.86 | ALDH1A1 (0.42) | ALDH1A1TP53CYP2C9CYP2C19LMNA | |
| SCHEMBL8042707 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TP53CYP2C19LMNAKMT2A | |
| SCHEMBL8044756 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TP53CYP2C9CYP2C19LMNA | |
| SCHEMBL8043987 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TP53CYP2C9CYP2C19LMNA | |
| SCHEMBL8046043 | 0.76 | HTT (0.42) | ALDH1A1TP53LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8033923 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TP53LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8710280 | 0.74 | CYP2C9 (0.44) | ALDH1A1TP53CYP2C9CYP2C19LMNA | |
| SCHEMBL8046039 | 0.74 | HSP90AA1 (0.46) | ALDH1A1TP53CYP2C9CYP2C19LMNA | |
| SCHEMBL8042600 | 0.73 | ALDH1A1 (0.35) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8032337 | 0.72 | HTT (0.39) | ALDH1A1CYP2C19LMNAKMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998027092-A1 | THIAZOLE COMPOUNDS AND METHODS OF MODULATING SIGNAL TRANSDUCTION | SUGEN, INC. (US) | 1998-06-25 | — | — | WO | disclosed |